Recovertendo is an innovative injectable medical solution specifically designed to treat pain and reduced mobility associated with tendon disorders. As a Class III infiltrative medical device, it leverages the synergistic action of two key components naturally found in the body: Bio-Adapted Hyaluronic Acid (BHA™) and Collagen Tripeptide (CTP).

 

Bio-Adapted Hyaluronic Acid (BHA™)

 

Hyaluronic Acid (HA) is a vital component of the extracellular matrix (ECM) in tendons, providing structural support and promoting tissue repair. Recovertendo's BHA™ is a physically stabilized form of HA, offering enhanced stability and longevity. Its unique purity, achieved through an exclusive patented manufacturing process utilizing microwave energy and CTP, ensures exceptional biocompatibility and minimal immune response at the injection site.

 

BHA™ functions in several crucial ways:

• Structural Support & Repair: It provides structural integrity and promotes tissue remodeling by filling tissue defects.

• Anti-inflammatory Action: HA possesses potent anti-inflammatory properties, modulating the inflammatory response to accelerate healing.

• Collagen Synthesis Stimulation: It stimulates the production of collagen, essential for restoring the biomechanical integrity of damaged tendons.

• Lubrication: BHA™ acts as a biological lubricant, minimizing inter-fiber friction during tendon movement and facilitating smooth, unhindered motion.

• Hydration: Its hygroscopic properties attract and retain water, maintaining crucial tissue hydration for optimal biomechanical properties and accelerated healing.

• ECM Quality & Cell Nutrition: BHA™ maintains ECM quality, improves cell lubrication and nutrition, and facilitates proteoglycan formation.

• Collagen Transformation & Fiber Alignment: It stimulates tenocytes and tenoblasts to increase collagen production, guides the conversion of unhealthy collagen type II to healthy collagen type I, and aids in correcting fiber alignment to reduce adhesions and scar tissue.

• Pain & Inflammation Reduction: By limiting inflammation and pain, BHA™ facilitates quicker and more effective tissue repair, accelerating recovery and restoring tendon strength and range of motion.

 

Collagen Tripeptide (CTP)

 

Collagen is the primary structural protein in tendons, providing essential tensile strength and resilience. Recovertendo incorporates synthetic Collagen Tripeptide (CTP), a minimum unit of collagen consisting of three amino acids (approx. 1/1,000th the size of a general collagen peptide). CTP plays a critical role in tendon health and repair:​

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• ECM and Fibrillar Structure Synthesis: It significantly contributes to the synthesis of ECM components and the establishment of the fibrillar structure, maintaining and repairing tissue integrity.

• Biomechanical Support: CTP supports tissue biomechanical properties through the upregulation of elastin (for elasticity) and integrin (for cell adhesion and signaling).

• Anti-inflammatory Effect: It exhibits anti-inflammatory properties, mitigating the inflammatory response after injury, which can expedite healing and reduce chronic inflammation.

• Glycine's Role: The high prevalence of glycine in CTP contributes to inhibiting pro-inflammatory cytokines and matrix metalloproteinases, preserving ECM integrity, and stimulating the synthesis of hydroxyproline, glycosaminoglycans, and non-collagenous proteins to enhance collagen organization.

• Proline-Hydroxyproline (Pro-Hyp) and Leucine: These components enhance collagen secretion in tenocytes and activate cells involved in tissue remodeling.

• 4-Hydroxyproline (Hyp)-containing Peptides: These peptides improve cellular homeostasis, promote differentiation and maturation of tendon cells, enhance cell proliferation, and promote type I collagen assembly.

 

The Synergistic Action

 

By combining the unique properties of Bio-Adapted Hyaluronic Acid and Collagen Tripeptide, Recovertendo provides a comprehensive approach to tendon healing. This optimized blend alleviates pain, acts as a lubricant, improves the mobility of injured tendons by reducing adhesions, and significantly speeds up the healing process by reducing inflammation. Recovertendo empowers you to regain your strength and function, leading to a quicker return to activity.